Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28328860 | 0.78 | CES1 (0.39) | ALDH1A1KMT2AMAPK1L3MBTL1TSHR | |
| SCHEMBL27999526 | 0.77 | TSHR (0.40) | ALDH1A1TSHR | |
| SCHEMBL27581285 | 0.77 | FABP7 (0.47) | FABP7FABP5P2RX4ALDH1A1KMT2A | |
| SCHEMBL28253699 | 0.75 | ATM (0.36) | ALDH1A1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL29797163 | 0.74 | RECQL (0.34) | ALDH1A1KMT2AMAPK1SLC6A2MEN1 | |
| SCHEMBL27541298 | 0.73 | ATM (0.42) | P2RX4ALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL7684001 | 0.72 | FABP7 (0.43) | FABP7FABP5ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19607654 | 0.70 | TSHR (0.44) | FABP7FABP5ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19607652 | 0.70 | TSHR (0.44) | FABP7FABP5ALDH1A1KMT2AMAPK1 | |
| SCHEMBL27580070 | 0.69 | P2RX4 (0.43) | FABP7FABP5P2RX4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431422-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2019-08-30 | — | — | CN | disclosed |
| CN-109456324-A | New isoindoline or isoquinoline compound, preparation method and the Pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-12 | — | — | CN | disclosed |
| CN-105408321-B | Indoles and azole derivatives, their preparation method and the pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-08 | — | — | CN | disclosed |
| CN-104341451-B | New phosphate compound, its preparation method and the pharmaceutical composition containing them | 瑟维尔实验室 | 2018-04-03 | — | — | CN | disclosed |
| CN-104341395-B | Novel azole compounds, process for their preparation and pharmaceutical compositions containing them | 瑟维尔实验室 | 2017-07-04 | — | — | CN | disclosed |
| CN-106674201-A | Pyrrole compounds, method of preparing same and pharmaceutical compositions containing the compounds | 法国施维雅药厂 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674196-A | Pyrrole compounds, method of preparing same and pharmaceutical compositions containing them | 法国施维雅药厂 | 2017-05-17 | — | — | CN | disclosed |
| CN-104144930-B | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | 瑟维尔实验室 | 2017-02-22 | — | — | CN | disclosed |