Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709072 | 0.81 | MMP2 (0.38) | APEX1PDK2CHRM2CHRM1CHRM3 | |
| SCHEMBL28125425 | 0.81 | MMP2 (0.38) | APEX1PDK2CHRM2CHRM1CHRM3 | |
| SCHEMBL4454321 | 0.80 | MMP2 (0.42) | APEX1PDK2ELANE | |
| SCHEMBL30110388 | 0.79 | APEX1 (0.50) | APEX1PDK2ELANEKDM4EPKM | |
| SCHEMBL1394531 | 0.79 | APEX1 (0.50) | APEX1PDK2ELANEKDM4EPKM | |
| SCHEMBL28799915 | 0.77 | APEX1 (0.48) | APEX1PDK2ELANEKDM4EPKM | |
| Benzene SCHEMBL27655081 | 0.77 | APEX1 (0.53) | APEX1PDK2ELANEKDM4EPKM | |
| SCHEMBL3931645 | 0.77 | APEX1 (0.37) | APEX1PDK2ELANEKDM4EPKM | |
| SCHEMBL30606694 | 0.77 | CYP2D6 (0.41) | APEX1PDK2ELANEKDM4EPKM | |
| SCHEMBL27756475 | 0.77 | CYP1A2 (0.38) | APEX1PDK2ELANEKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242938-A | Fluorene ethylene derivative and synthetic method thereof | 沈阳大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | disclosed |