Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17950628 | 0.85 | NPSR1 (0.51) | KDM4ELMNAGFERNPSR1ALDH1A1 | |
| SCHEMBL17950213 | 0.82 | TDP1 (0.48) | KDM4ELMNAGFERNPSR1ALDH1A1 | |
| SCHEMBL21503265 | 0.74 | KDM4E (0.47) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL1304462 | 0.72 | KDM4E (0.48) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL17107907 | 0.71 | KDM4E (0.47) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL13977598 | 0.71 | KDM4E (0.49) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL22535987 | 0.71 | TDP1 (0.46) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL13977597 | 0.70 | KDM4E (0.49) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL17107898 | 0.70 | L3MBTL1 (0.50) | KDM4ELMNAGFERNPSR1L3MBTL1 | |
| SCHEMBL18522580 | 0.70 | CA1 (0.38) | KDM4ELMNAGFERL3MBTL1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-106164072-A | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2016-11-23 | — | — | CN | disclosed |