SCHEMBL2811080

SCHEMBL2811080

CCCCCCc1cc(C)ccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 9/20 0.58
PLK3 Q9H4B4 2/20 0.55
PPARA Q07869 2/20 0.55
RARB P10826 3/20 0.54
KAT8 Q9H7Z6 2/20 0.51
PPARG P37231 1/20 0.51
RARA P10276 1/20 0.50
RARG P13631 1/20 0.50
HPSE Q9Y251 1/20 0.49
TRPM2 O94759 1/20 0.48
BID P55957 1/20 0.48
BCL2L1 Q07817 1/20 0.48
MCL1 Q07820 1/20 0.48
BAK1 Q16611 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13176935 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL27889924 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL27889926 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL27906431 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL28807894 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL9342043 1.00 PLK1 (0.58) PLK1PLK3PPARARARBKAT8
SCHEMBL2808363 0.98 PLK1 (0.56) PLK1PLK3PPARARARBKAT8
SCHEMBL2807445 0.93 GABRP (0.53) PLK1PLK3PPARARARBPPARG
SCHEMBL5696657 0.93 PLK1 (0.49) PLK1PLK3PPARARARBPPARG
SCHEMBL7774557 0.92 CSNK2A1 (0.50) PLK1PLK3PPARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US claimed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO claimed
EP-3260920-A1 TONER COMPOSITIONS WITH ANTIPLASTICIZERS Xerox Corporation (US) 2017-12-27 EP disclosed
US-9684257-B1 Toner compositions with antiplasticizers XEROX CORPORATION (US) 2017-06-20 US disclosed
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US disclosed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO disclosed