Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291368 | 0.85 | PDE5A (0.62) | PDE5AMEN1KMT2A | |
| SCHEMBL16372093 | 0.73 | PDE5A (0.56) | PDE5AMEN1KMT2A | |
| SCHEMBL28111576 | 0.70 | PDE5A (0.50) | PDE5AGPR39PTGS2PTGS1 | |
| SCHEMBL28798098 | 0.70 | PDE5A (0.49) | PDE5AGPR39PTGS2PTGS1 | |
| SCHEMBL290571 | 0.70 | PDE5A (0.63) | PDE5AGPR39MEN1KMT2A | |
| SCHEMBL292253 | 0.69 | PDE5A (0.62) | PDE5AMEN1KMT2A | |
| SCHEMBL291267 | 0.67 | PDE5A (0.56) | PDE5AGPR39PTGS2 | |
| SCHEMBL290819 | 0.67 | PDE5A (0.68) | PDE5AMEN1KMT2A | |
| SCHEMBL291579 | 0.66 | PDE5A (0.62) | PDE5AMEN1KMT2A | |
| SCHEMBL6068427 | 0.66 | PDE5A (0.71) | PDE5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106038567-A | Treatment of addiction and impulse-control disorders using pde7 inhibitors | 奥默罗斯公司 | 2016-10-26 | — | — | CN | disclosed |