Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 16/20 | 0.73 |
| ▸ | F9 | P00740 | 2/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18604646 | 0.92 | KLKB1 (0.70) | KLKB1 | |
| SCHEMBL18605123 | 0.92 | KLKB1 (0.80) | KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL18604821 | 0.91 | KLKB1 (0.69) | KLKB1 | |
| SCHEMBL20579701 | 0.86 | KLKB1 (0.82) | KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL17064369 | 0.84 | KLKB1 (0.94) | KLKB1 | |
| SCHEMBL18604682 | 0.84 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18604998 | 0.84 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL18604801 | 0.84 | KLKB1 (0.90) | KLKB1 | |
| SCHEMBL31744211 | 0.83 | KLKB1 (1.00) | KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL17064981 | 0.83 | KLKB1 (1.00) | KLKB1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |