Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 6/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875828 | 0.90 | SRC (0.52) | ALDH1A1CTNNB1TCF7L2SRCABL1 | |
| SCHEMBL2786942 | 0.83 | HRH4 (0.54) | ALDH1A1SRCABL1PDE5AHRH4 | |
| SCHEMBL2835632 | 0.81 | BCDIN3D (0.52) | PDE2AALDH1A1CTNNB1TCF7L2SRC | |
| SCHEMBL2810687 | 0.80 | PIK3CA (0.54) | ALDH1A1SRCABL1USP2RAB9A | |
| SCHEMBL3640038 | 0.79 | APP (0.64) | ALDH1A1CTNNB1TCF7L2PDE5AHRH4 | |
| SCHEMBL3644324 | 0.78 | CTNNB1 (0.64) | ALDH1A1CTNNB1TCF7L2PDE5AHRH4 | |
| SCHEMBL3644693 | 0.78 | HTR2C (0.58) | PDE2APDE5AHRH4PDE4APDE4B | |
| SCHEMBL2814606 | 0.75 | CDK1 (0.42) | PDE2AALDH1A1 | |
| SCHEMBL2871542 | 0.74 | PDE5A (0.51) | ALDH1A1SRCABL1USP2RAB9A | |
| SCHEMBL2807943 | 0.73 | SRC (0.68) | SRCABL1USP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |