Chlorobenzene

Chlorobenzene

SCHEMBL28111876

Clc1ccccc1.O=P(Cl)(Cl)Cl

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.69
CYP1A2 P05177 2/20 0.48
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
HPGD P15428 1/20 0.42
ACP3 P15309 1/20 0.42
LMNA P02545 2/20 0.41
CYP2A6 P11509 1/20 0.41
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
PTGS2 P35354 2/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL6285547 0.85 TSHR (0.65) TSHRCYP1A2CES2CES1ACP3
Chlorobenzene SCHEMBL31175844 0.85 TSHR (0.65) TSHRCYP1A2CES2CES1ACP3
Chlorobenzene SCHEMBL11220629 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1LMNA
Chlorobenzene SCHEMBL9721018 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1LMNA
Chlorobenzene SCHEMBL1339852 0.83
Chlorobenzene SCHEMBL2168046 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1LMNA
SCHEMBL24715429 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1LMNA
Chlorobenzene SCHEMBL1330702 0.83
Chlorobenzene SCHEMBL1568605 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1LMNA
Chlorobenzene SCHEMBL1331798 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118272956-A Breathable, hygroscopic and flame-retardant polyurethane fiber as well as preparation and application thereof 江苏恒科新材料有限公司 2024-07-02 CN claimed
CN-118272956-A Breathable, hygroscopic and flame-retardant polyurethane fiber as well as preparation and application thereof 江苏恒科新材料有限公司 2024-07-02 CN disclosed
CN-110426917-A Photosensitive laminate and its manufacturing method ASAHI KASEI CORP 2019-11-08 CN disclosed
CN-109824580-A A method of preparing chloro--methylpyridine 江苏扬农化工集团有限公司 2019-05-31 CN disclosed
CN-106117128-B A kind of method that micro passage reaction continuously prepares pyridone chlorine addition product 江苏扬农化工集团有限公司 2018-12-28 CN disclosed
CN-106117128-A A kind of micro passage reaction prepares the method for pyridone chlorine addition product continuously 江苏扬农化工集团有限公司 2016-11-16 CN disclosed