Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161933 | 0.89 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL29635738 | 0.89 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL29635626 | 0.88 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL175663 | 0.88 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL28162252 | 0.86 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL165510 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL163921 | 0.85 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635741 | 0.85 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635895 | 0.85 | NAMPT (0.77) | NAMPTCYP2C9 | |
| SCHEMBL164531 | 0.85 | NAMPT (0.77) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103270023-B | 4- { [ (pyridin-3-yl-methyl) aminocarbonyl ] amino } benzene-sulfone derivatives as NAMPT inhibitors for the treatment of diseases such as cancer | 福马TM有限责任公司 | 2016-11-02 | — | — | CN | claimed |
| CN-106986856-A | It is used as 4 { [(ylmethyl of pyridine 3) amino carbonyl] amino } Benzosulfone derivatives of the NAMPT inhibitor for treating diseases such as cancer | 福马TM有限责任公司 | 2017-07-28 | — | — | CN | disclosed |