SCHEMBL28111935

SCHEMBL28111935

N/C(=N\O)c1ccc(/C=C/c2cc(O)c(O)cc2F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 17/20 1.00
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
KCNH2 Q12809 1/20 0.40
NFE2L2 Q16236 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31236624 0.82 KDM1A (1.00) KDM1A
SCHEMBL28111447 0.82 KDM1A (1.00) KDM1A
SCHEMBL28836347 0.80 KDM1A (1.00) KDM1A
SCHEMBL28111933 0.75 KDM1A (0.59) KDM1AHTR2AHTR2CKCNH2NFE2L2
SCHEMBL28111408 0.74 KDM1A (0.58) KDM1ANFE2L2
SCHEMBL28111407 0.74 KDM1A (0.58) KDM1ANFE2L2
SCHEMBL2772394 0.69 KDM1A (0.68) KDM1A
SCHEMBL20580081 0.69 KDM1A (0.68) KDM1A
SCHEMBL31558284 0.68 KDM1A (1.00) KDM1A
SCHEMBL28111533 0.67 KDM1A (1.00) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106045881-A Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor 新乡医学院 2016-10-26 CN disclosed