Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111407 | 1.00 | KDM1A (0.58) | KDM1ANFE2L2TRPA1NQO2PTGS1 | |
| SCHEMBL9235723 | 0.84 | NFE2L2 (0.65) | NFE2L2TRPA1 | |
| SCHEMBL9235728 | 0.84 | NFE2L2 (0.65) | NFE2L2TRPA1 | |
| SCHEMBL30842462 | 0.82 | AHR (0.51) | KDM1ANFE2L2TRPA1PTGS1AHR | |
| SCHEMBL13339166 | 0.79 | TRPA1 (0.65) | NFE2L2TRPA1PTGS1AHR | |
| SCHEMBL308225 | 0.78 | TRPA1 (0.59) | NFE2L2TRPA1PTGS1AHR | |
| SCHEMBL28194187 | 0.78 | TRPA1 (0.59) | NFE2L2TRPA1PTGS1AHR | |
| SCHEMBL7139129 | 0.78 | TRPA1 (0.59) | NFE2L2TRPA1PTGS1AHR | |
| SCHEMBL28111394 | 0.77 | KDM1A (0.58) | KDM1ANFE2L2TRPA1PTGS1AHR | |
| SCHEMBL20220096 | 0.77 | NFE2L2 (0.57) | NFE2L2TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045881-A | Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor | 新乡医学院 | 2016-10-26 | — | — | CN | disclosed |