Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258478 | 0.78 | GAA (0.42) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL27728514 | 0.78 | GAA (0.61) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL27908656 | 0.76 | GAA (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL204758 | 0.76 | GAA (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL27807390 | 0.74 | GAA (0.48) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL197340 | 0.74 | MGAM (0.48) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL8920059 | 0.74 | GAA (0.48) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL3441102 | 0.73 | MGAM (0.69) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL53913 | 0.73 | — | — | |
| SCHEMBL27449382 | 0.72 | TRPA1 (0.40) | GAAMGAMSIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467492-A | The preparation method of polyfluoro methyl pyrazoles compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2017-03-01 | — | — | CN | disclosed |