Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328 | 0.83 | PDE4D (0.65) | PDE4DGAAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL28112046 | 0.83 | PDE4D (0.42) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL20075372 | 0.82 | PDE4D (0.39) | PDE4DMAPK1ALDH1A1NPSR1LMNA | |
| SCHEMBL22637869 | 0.80 | PDE4D (0.38) | PDE4DMAPK1LMNAKDM4EMEN1 | |
| SCHEMBL4754626 | 0.77 | PDE4D (0.66) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL11205284 | 0.74 | PDE4D (0.47) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL11201220 | 0.73 | PDE4D (0.46) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL10720445 | 0.73 | PDE4D (0.46) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL17777759 | 0.73 | PDE4D (0.46) | PDE4DGAAARHSP90AA1HSP90AB1 | |
| SCHEMBL23301792 | 0.72 | PDE4D (0.42) | PDE4DGAAARHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467492-B | preparation method of polyfluoromethyl pyrazole compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-106467492-A | The preparation method of polyfluoro methyl pyrazoles compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2017-03-01 | — | — | CN | disclosed |