Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL7257189 | 0.92 | LMNA (0.65) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL28198360 | 0.92 | LMNA (0.65) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL29103073 | 0.86 | LMNA (0.58) | LMNATSHRACHEALOX12CES2 | |
| Toluene SCHEMBL28182062 | 0.83 | LMNA (0.61) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL28217510 | 0.82 | LMNA (0.52) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL27629161 | 0.81 | LMNA (0.58) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL27848238 | 0.81 | HPGD (0.71) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL10856877 | 0.80 | LMNA (0.65) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL1011089 | 0.80 | LMNA (0.65) | LMNATSHRACHEALOX12HPGD | |
| Toluene SCHEMBL695755 | 0.80 | LMNA (0.65) | LMNATSHRACHEALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146551-A | The preparation method of insecticide orthene | 江苏蓝丰生物化工股份有限公司 | 2016-11-23 | — | — | CN | disclosed |