Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 10/20 | 0.71 |
| ▸ | TNKS2 | Q9H2K2 | 10/20 | 0.71 |
| ▸ | PARP1 | P09874 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | GUSB | P08236 | 7/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764055 | 1.00 | TNKS (0.71) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL6885282 | 0.84 | TNKS (0.93) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL29764113 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL7765127 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL8620410 | 0.83 | TNKS (0.83) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL11078929 | 0.82 | NPC1 (1.00) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL29593073 | 0.82 | NPC1 (1.00) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL4505299 | 0.82 | TNKS (0.71) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL29784025 | 0.82 | TNKS (0.71) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL28639676 | 0.82 | NPC1 (0.78) | TNKSTNKS2PARP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185468-B | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-113185468-A | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112645887-A | Preparation method of quinazolinone derivative | 淮阴工学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-106518789-B | A method of synthesis Quinazol derivative | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106518789-A | Method for synthesis of quinazolinone derivative | 南京理工大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106478525-A | A kind of method of synthesis quinazolone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |