SCHEMBL2811339

SCHEMBL2811339

COc1ccccc1OC=C(C)C(=Nc1ccc(C)c(C)c1)Sc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QRFPR Q96P65 2/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMO Q99835 2/20 0.32
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811338 1.00 QRFPR (0.36) QRFPRMEN1KMT2AHTR3EHTR3B
SCHEMBL2813255 0.87 MAPT (0.41) QRFPRMEN1KMT2AHTR3EHTR3B
SCHEMBL2813258 0.87 MAPT (0.41) QRFPRMEN1KMT2AHTR3EHTR3B
SCHEMBL2816113 0.87 NOS3 (0.37) QRFPRKMT2AHTR3EHTR3BHTR3A
SCHEMBL12851012 0.87 NOS3 (0.37) QRFPRKMT2AHTR3EHTR3BHTR3A
SCHEMBL2816116 0.87 NOS3 (0.37) QRFPRKMT2AHTR3EHTR3BHTR3A
SCHEMBL12850917 0.86 CDC25A (0.34) MEN1KMT2ACDC25ACDC25BMAPT
SCHEMBL2809339 0.86 CDC25A (0.34) MEN1KMT2ACDC25ACDC25BMAPT
SCHEMBL2809336 0.86 CDC25A (0.34) MEN1KMT2ACDC25ACDC25BMAPT
SCHEMBL2815813 0.85 NOS3 (0.42) QRFPRMEN1KMT2AHTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 QRFPR 938/4885MEN1 3112/4885KMT2A 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.