Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 6/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435005 | 0.75 | PLA2G10 (0.44) | BACE1APPPLA2G10GRM2MAPT | |
| SCHEMBL28113101 | 0.74 | HTR2A (0.36) | MAPT | |
| SCHEMBL15881998 | 0.73 | POLB (0.36) | PLA2G10 | |
| SCHEMBL16796416 | 0.72 | TP53 (0.37) | GRM2MAPT | |
| SCHEMBL17454469 | 0.70 | BAZ2B (0.33) | PLA2G10 | |
| SCHEMBL16796439 | 0.68 | PTGER1 (0.39) | — | |
| SCHEMBL1554076 | 0.68 | SCN4A (0.42) | SCN9AMAPT | |
| SCHEMBL17452579 | 0.68 | BAZ2B (0.32) | — | |
| SCHEMBL8433063 | 0.68 | MAPK1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL16796434 | 0.68 | PTGER1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |