Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113595 | 0.87 | HTR2A (0.39) | HTR2AHTR2CSLC6A4SMN1; SMN2CNR1 | |
| SCHEMBL16796416 | 0.84 | TP53 (0.37) | HTR2AHTR2CSLC6A4SMN1; SMN2P2RY14 | |
| SCHEMBL17610952 | 0.84 | HTR2A (0.42) | HTR2AHTR2CSLC6A4SMN1; SMN2KDM4E | |
| SCHEMBL16806831 | 0.80 | GUCY1B2 (0.33) | PTGER1P2RY14 | |
| Hydrochloric Acid SCHEMBL16796430 | 0.79 | F2 (0.34) | — | |
| SCHEMBL16796439 | 0.78 | PTGER1 (0.39) | SMN1; SMN2KDM4EPTGER1 | |
| Hydrochloric Acid SCHEMBL16796434 | 0.77 | PTGER1 (0.38) | SMN1; SMN2KDM4EPTGER1 | |
| SCHEMBL10330274 | 0.75 | PTGER1 (0.49) | KDM4EPTGER1P2RY14CYP2C19MEN1 | |
| Fluorobenzene SCHEMBL28113596 | 0.74 | THRB (0.32) | MAPT | |
| SCHEMBL16796413 | 0.73 | P2RY14 (0.39) | HTR2AHTR2CSLC6A4SMN1; SMN2P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |