Urea

Urea

SCHEMBL28113656

NC(N)=O.O=P(O)(O)OF

nearest known ligand 0.50

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.50
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
OR51E2 Q9H255 1/20 0.40
FDPS P14324 1/20 0.39
BLM P54132 1/20 0.39
TPI1 P60174 1/20 0.39
CA1 P00915 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
PGD P52209 1/20 0.34
PEPD P12955 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88353 0.86
SCHEMBL27863157 0.86 FDPS (0.50) CA4TDP1FDPSBLMTPI1
SCHEMBL27462858 0.83
SCHEMBL9147655 0.82
SCHEMBL22287248 0.82
SCHEMBL15136237 0.82
Hydrogen Sulfide SCHEMBL19182707 0.82
SCHEMBL20593987 0.82
SCHEMBL7097940 0.82
Water SCHEMBL17318092 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146502-A End for Larry this synthetic method and prepare intermediate 上海医药工业研究院 2016-11-23 CN claimed
CN-117279910-A Modulators of BCL6 proteolysis and related methods of use 阿尔维纳斯运营股份有限公司 2023-12-22 CN disclosed