Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28075164 | 0.91 | TDP1 (0.55) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL28128452 | 0.91 | TDP1 (0.55) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL5694604 | 0.91 | TDP1 (0.55) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL2703945 | 0.91 | TDP1 (0.55) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL28214512 | 0.89 | TDP1 (0.52) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL27994753 | 0.85 | TDP1 (0.48) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL28748230 | 0.85 | TDP1 (0.39) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL28086274 | 0.83 | TDP1 (0.46) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL28264839 | 0.83 | TP53 (0.50) | TDP1CA2CA12CA1GLA | |
| Phenol SCHEMBL10454590 | 0.82 | GLA (0.55) | TDP1CA2CA12CA1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106332460-A | High-precision circuit and preparation method thereof | 中国科学院化学研究所 | 2017-01-11 | — | — | CN | claimed |