Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28075164 | 0.91 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28128452 | 0.91 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL2703945 | 0.91 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL5694604 | 0.91 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28214512 | 0.89 | TDP1 (0.52) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27994753 | 0.85 | TDP1 (0.48) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL1668893 | 0.84 | TDP1 (0.42) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28113945 | 0.83 | TDP1 (0.46) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27496048 | 0.82 | TDP1 (0.44) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28189602 | 0.80 | CA12 (0.58) | TDP1CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103926641-B | Color composition for color filter and color filter | 东洋油墨SC控股株式会社 | 2016-07-06 | — | — | CN | disclosed |