Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762335 | 0.87 | SIRT2 (0.50) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL9429347 | 0.86 | DDX3X (0.56) | MAPK10TP53NPSR1GAADDX3X | |
| SCHEMBL881130 | 0.86 | SIRT2 (0.64) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL18383359 | 0.85 | SIRT2 (0.49) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL20108954 | 0.85 | ABCG2 (0.49) | MAPK10TP53PKMPKLRGAA | |
| SCHEMBL18383212 | 0.84 | SIRT2 (0.48) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL20010757 | 0.82 | GAA (0.54) | MAPK10EPHX2TP53GAAKDM4E | |
| SCHEMBL21992221 | 0.82 | CNR1 (0.45) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL25637578 | 0.82 | SIRT2 (0.50) | SIRT2SIRT1AKR1C3EPHX2MGLL | |
| SCHEMBL17858148 | 0.82 | PTGER4 (0.49) | AKR1C3MAPK10EPHX2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170474-B | Novel compound | 出光兴产株式会社 | 2018-11-06 | — | — | CN | disclosed |
| CN-106170474-A | Novel compound | 出光兴产株式会社 | 2016-11-30 | — | — | CN | disclosed |