SCHEMBL28114301

SCHEMBL28114301

C[SiH](C)N[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12273825 0.83 TDP1 (0.35) TSHRLMNAALOX12ACHE
SCHEMBL18143562 0.72 TSHR (0.35) TSHRLMNAALOX12ACHEKCNN4
SCHEMBL2268375 0.72 TSHR (0.41) TSHRLMNAALOX12ACHEKCNN4
SCHEMBL124751 0.67 TSHR (0.39) TSHRLMNAALOX12ACHE
SCHEMBL55166 0.67
SCHEMBL1539360 0.67 TSHR (0.39) TSHRLMNAALOX12ACHE
SCHEMBL2542387 0.67 TSHR (0.35) TSHRALOX12
Dimethylamine SCHEMBL10623601 0.67 TSHR (0.41) TSHRLMNAALOX12ACHEKCNN4
SCHEMBL2268660 0.67 KCNN4 (0.38) TSHRLMNAALOX12KCNN4
SCHEMBL842866 0.67 MAPK1 (0.37) TSHRLMNAKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732602-A Preparation method of silazane 浙江新安化工集团股份有限公司 2020-10-02 CN disclosed
CN-106317101-A Method for synthesizing 1,3-di(diphenylchlorosilyl)-2,2,4,4-tetramethylcyclodisilazane by non-high-temperature exchange process 中国科学院化学研究所 2017-01-11 CN disclosed