Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | GLB1 | P16278 | 2/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129740 | 1.00 | S1PR1 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL15155327 | 1.00 | S1PR1 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL9751519 | 1.00 | S1PR1 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL11648543 | 1.00 | S1PR1 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL10797222 | 1.00 | S1PR1 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL8200564 | 0.98 | CXCR4 (0.44) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL9187514 | 0.98 | CXCR4 (0.44) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL21010237 | 0.98 | CXCR4 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL1638947 | 0.98 | CXCR4 (0.42) | S1PR1S1PR3CXCR4GBA1SPHK1 | |
| SCHEMBL17344117 | 0.96 | CXCR4 (0.45) | S1PR1S1PR3CXCR4GBA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244948-B | Compositions and methods for modulating specific amidases of N-acylethanolamines for use in the treatment of inflammatory diseases | 爱普泰克集团有限公司 | 2016-11-16 | — | — | CN | disclosed |