Toluene

Toluene

SCHEMBL28114367

CC1(C)c2ccccc2-c2cc(Br)ccc21.Cc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.41
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
PGR P06401 2/20 0.38
PDE4B Q07343 1/20 0.37
PTPRC P08575 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
ACHE P22303 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL806937 0.91 PDK2 (0.46) PDK2MAPK1PDE4BPTPRCTDP1
SCHEMBL29564362 0.91 PDK2 (0.46) PDK2MAPK1PDE4BPTPRCTDP1
SCHEMBL25937351 0.90 PTPRC (0.46) PDK2MAPK1PDE4BPTPRCTDP1
SCHEMBL21436406 0.86 PDK2 (0.50) PDK2MAPK1PDE4BPTPRCTDP1
SCHEMBL805016 0.82 S100A4 (0.41) PDK2ALDH1A1PGRPDE4BPTPRC
SCHEMBL30567840 0.82 S100A4 (0.41) PDK2ALDH1A1PGRPDE4BPTPRC
SCHEMBL14174206 0.81 PDK2 (0.51) PDK2ALDH1A1PGRPTPRCTDP1
SCHEMBL26157455 0.81 PDK2 (0.42) PDK2PTPRCTDP1L3MBTL1
SCHEMBL20225271 0.81 PDK2 (0.39) PDK2MAPK1PDE4BPTPRCLMNA
SCHEMBL23923645 0.80 PDK2 (0.46) PDK2MAPK1PDE4BPTPRCTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103718317-B Material for electronic devices 默克专利有限公司 2016-11-16 CN disclosed