Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895580 | 1.00 | PPARA (0.58) | PPARAPPARGSLC1A3SLC1A1ITGB3 | |
| SCHEMBL11414810 | 1.00 | PPARA (0.58) | PPARAPPARGSLC1A3SLC1A1ITGB3 | |
| SCHEMBL2748240 | 0.92 | PPARA (0.65) | PPARAPPARGITGB3ITGA2BCTSK | |
| SCHEMBL7354938 | 0.92 | PPARA (0.65) | PPARAPPARGITGB3ITGA2BCTSK | |
| SCHEMBL6835795 | 0.92 | PPARA (0.65) | PPARAPPARGITGB3ITGA2BCTSK | |
| SCHEMBL6835796 | 0.92 | PPARA (0.65) | PPARAPPARGITGB3ITGA2BCTSK | |
| SCHEMBL11288175 | 0.91 | KYNU (0.54) | PPARAPPARGSLC1A3SLC1A1CTSK | |
| SCHEMBL9346829 | 0.90 | MME (0.52) | PPARAPPARGCASP1CTSL | |
| SCHEMBL11185687 | 0.90 | PPARA (0.64) | PPARAPPARGSLC1A3SLC1A1ITGB3 | |
| SCHEMBL2874299 | 0.89 | PPARA (0.47) | PPARAPPARGSLC1A3SLC1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106163568-A | Antibody drug conjugates (ADC) containing spindle kinesin (KSP) | 拜耳制药股份公司 | 2016-11-23 | — | — | CN | disclosed |