SCHEMBL28114466

SCHEMBL28114466

C(=NOCc1ccccc1)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
MAPT P10636 5/20 0.60
L3MBTL1 Q9Y468 4/20 0.60
GAA P10253 3/20 0.60
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 2/20 0.60
THRB P10828 1/20 0.60
PKM P14618 1/20 0.60
CASP3 P42574 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
PLEC Q15149 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
PPARG P37231 1/20 0.59
PPARA Q07869 1/20 0.59
RAB9A P51151 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798007 0.86 NPC1 (0.70) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL3080186 0.86 NPC1 (0.70) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL3080187 0.86 NPC1 (0.70) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL28114962 0.85 KDM4E (0.58) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL12757029 0.85 KDM4E (0.58) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL3110984 0.82 GSK3B (0.54) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL3110979 0.82 GSK3B (0.54) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL2297148 0.81 RAB9A (0.71) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL17625509 0.81 MEN1 (0.66) KMT2AMEN1MAPTL3MBTL1GAA
SCHEMBL189965 0.81 RAB9A (0.71) KMT2AMEN1MAPTL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106187816-B A kind of fracture based on C N keys is come the method for synthesizing oxime ether class compound 南开大学 2018-03-27 CN disclosed
CN-106187816-A A kind of method that fracture based on C N key carrys out synthesizing oxime ether compounds 南开大学 2016-12-07 CN disclosed