Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819135 | 0.85 | KMT2A (0.60) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9136568 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL11144552 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL1828950 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL3164500 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL28760524 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL28792430 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL6358511 | 0.79 | MAPT (0.56) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL21262429 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9847377 | 0.79 | MAPT (0.57) | ALDH1A1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104099353-B | Regioselective bacterial nitroreductase gene, recombinase thereof and application thereof | 大连理工大学 | 2017-01-11 | — | — | CN | disclosed |