Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019945 | 0.86 | PPARA (0.47) | PPARAPPARGMAPTALDH1A1HPGD | |
| SCHEMBL6580876 | 0.84 | MAPT (0.44) | PPARAPPARGMAPTALDH1A1HPGD | |
| SCHEMBL16563569 | 0.80 | LMNA (0.41) | ALDH1A1LMNAMAPK1HTTRAB9A | |
| SCHEMBL27375655 | 0.80 | CA12 (0.50) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL28114753 | 0.79 | EPHX2 (0.51) | MAPTALDH1A1HPGDTSHRGAA | |
| SCHEMBL13064649 | 0.79 | TSHR (0.43) | PPARAPPARGMAPTALDH1A1HPGD | |
| SCHEMBL26231913 | 0.78 | LMNA (0.46) | PPARAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL31063303 | 0.77 | NCOA1 (0.46) | MAPTALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL9804351 | 0.77 | CES1 (0.41) | LMNAMAPK1HTTRAB9AEPHX2 | |
| SCHEMBL12780439 | 0.76 | MAPT (0.44) | MAPTALDH1A1HPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245698-B | Nitrogen-containing heterocyclic compound | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-11-30 | — | — | CN | disclosed |