Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | NQO2 | P16083 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | CFTR | P13569 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898722 | 0.87 | ABL1 (0.46) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL28722488 | 0.84 | KDM4E (0.50) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL176841 | 0.82 | ABL1 (0.64) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL36846569 | 0.82 | ABL1 (0.64) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL28665944 | 0.81 | KDM4E (0.59) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL25612414 | 0.81 | ABL1 (0.53) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL21527283 | 0.79 | SOS1 (0.43) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL358224 | 0.79 | CFTR (0.49) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL3574538 | 0.79 | GAA (0.49) | ABL1GAANQO2KDM4ECFTR | |
| SCHEMBL13280601 | 0.79 | ABL1 (0.51) | ABL1GAANQO2KDM4ECFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-104812749-B | Indolecarboxamide derivant as P2X7 receptor antagonist | 埃科特莱茵药品有限公司 | 2016-12-14 | — | — | CN | disclosed |