Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenpiclonil SCHEMBL29416541 | 0.98 | DYRK1A (0.44) | DYRK1ACNR2CNR1METKDR | |
| Fenpiclonil SCHEMBL22130 | 0.98 | DYRK1A (0.44) | DYRK1ACNR2CNR1METKDR | |
| Fenpiclonil SCHEMBL7523941 | 0.98 | DYRK1A (0.44) | DYRK1ACNR2CNR1METKDR | |
| Fenpiclonil SCHEMBL5426061 | 0.87 | PIM1 (0.39) | DYRK1ACNR2CNR1METKDR | |
| SCHEMBL30343613 | 0.84 | LRRK2 (0.50) | DYRK1ALRRK2ALOX15TSHRAR | |
| SCHEMBL6435410 | 0.84 | LRRK2 (0.50) | DYRK1ALRRK2ALOX15TSHRAR | |
| SCHEMBL7902072 | 0.82 | DYRK1A (0.41) | DYRK1ALRRK2ARKDM4E | |
| SCHEMBL28442816 | 0.82 | CHUK (0.37) | DYRK1ACNR2CNR1LRRK2AR | |
| Fludioxonil SCHEMBL5072145 | 0.80 | CNR2 (0.33) | DYRK1ACNR2CNR1ALOX15 | |
| SCHEMBL9458508 | 0.78 | AR (0.43) | ARKDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132422-A | Adoptive cell therapy using agonists of retinoic acid receptor-associated orphan receptor gamma & related therapeutic methods | 莱斯拉公司 | 2016-11-16 | — | — | CN | disclosed |