Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenpiclonil SCHEMBL22130 | 0.83 | DYRK1A (0.44) | DYRK1ALRRK2ARL3MBTL1MCL1 | |
| Fenpiclonil SCHEMBL7523941 | 0.83 | DYRK1A (0.44) | DYRK1ALRRK2ARL3MBTL1MCL1 | |
| Fenpiclonil SCHEMBL29416541 | 0.83 | DYRK1A (0.44) | DYRK1ALRRK2ARL3MBTL1MCL1 | |
| SCHEMBL11937467 | 0.83 | BCAT1 (0.49) | DYRK1ALRRK2CYP11B2MCL1CHUK | |
| SCHEMBL30343613 | 0.83 | LRRK2 (0.50) | DYRK1ALRRK2ARL3MBTL1KDM4E | |
| SCHEMBL6435410 | 0.83 | LRRK2 (0.50) | DYRK1ALRRK2ARL3MBTL1KDM4E | |
| Fenpiclonil SCHEMBL28114908 | 0.82 | DYRK1A (0.42) | DYRK1ALRRK2ARKDM4E | |
| SCHEMBL24084247 | 0.81 | ADORA2A (0.43) | DYRK1AKMOLRRK2ARL3MBTL1 | |
| SCHEMBL28442816 | 0.81 | CHUK (0.37) | DYRK1ALRRK2ARCYP11B2CHUK | |
| SCHEMBL10334044 | 0.81 | DYRK1A (0.32) | DYRK1ALRRK2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423566-B1 | FUNGICIDAL COMBINATION OF ACTIVE AGENTS | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| US-5059616-A | Fungicidal combinations of active compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-22 | — | — | US | claimed |
| EP-0423566-A1 | Fungicidal combination of active agents | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| US-4965363-A | REACTING 2-(2-FLUORO-3-CHLOROPHENYLMETHYLIDENE)CYANACETAMIDE WITH A SULFONYLMETHYLISOCYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | claimed |
| EP-0327987-A1 | 1-Aminomethyl-3-(2-fluoro-3-chlorophenyl)-4-cyano-pyrrole derivatives | BAYER AG (DE) | 1989-08-16 | — | — | EP | claimed |
| JP-3133908-A | — | — | None | — | — | JP | disclosed |
| JP-1228958-A | — | — | None | — | — | JP | disclosed |
| US-6204397-B1 | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0505742-B1 | Process for the production of 4-cyanopyrrole compounds substituted at the 3-position | BAYER AG (DE) | 2000-09-20 | — | — | EP | disclosed |
| EP-0324336-B2 | Process for the preparation of 3-cyano-4-aryl-pyrroles | BAYER AG (DE) | 1995-11-08 | — | — | EP | disclosed |
| US-5258526-A | Reacting aromatic bromide with acrylonitrile followed by cyclizing with a phenylsulphonylmethyl isocyanide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0423566-B1 | FUNGICIDAL COMBINATION OF ACTIVE AGENTS | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-4965363-A | REACTING 2-(2-FLUORO-3-CHLOROPHENYLMETHYLIDENE)CYANACETAMIDE WITH A SULFONYLMETHYLISOCYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4960789-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0339417-A1 | 3-Cyano-4-phenyl-pyrroles | BAYER AG (DE) | 1989-11-02 | — | — | EP | disclosed |
| JP-H01228958-A | 1-AMINOMETHYL-3-(2-FLUORO-3-CHLOROPHENYL)-4-CYANO-PYRROLE DERIVATIVE | BAYER AG | 1989-09-12 | — | — | JP | disclosed |
| EP-0327987-A1 | 1-Aminomethyl-3-(2-fluoro-3-chlorophenyl)-4-cyano-pyrrole derivatives | BAYER AG (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0327987-A1 | 1-Aminomethyl-3-(2-fluoro-3-chlorophenyl)-4-cyano-pyrrole derivatives | BAYER AG (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0324336-A2 | Process for the preparation of 3-cyano-4-aryl-pyrroles | BAYER AG (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0318704-A2 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |