SCHEMBL28115345

SCHEMBL28115345

CC(NC(=S)Nc1ccccc1)C1CNCCO1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
EPHX2 P34913 1/20 0.44
CAPN1 P07384 3/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
SSTR4 P31391 1/20 0.42
SLC6A2 P23975 8/20 0.41
SLC6A4 P31645 7/20 0.41
SLC6A3 Q01959 6/20 0.41
MLNR O43193 1/20 0.41
ADRB2 P07550 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2C P28335 1/20 0.41
OPRK1 P41145 1/20 0.41
KCNH2 Q12809 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27775413 0.74 SLC6A2 (0.47) ALDH1A1SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL29084651 0.73 SLC6A2 (0.46) ALDH1A1SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL27978405 0.72 SLC6A2 (0.41) GAASSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL28115374 0.72 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2MEN1CYP3A4CYP2C9
SCHEMBL28115344 0.71 GAA (0.50) ALDH1A1LMNAGAASMN1; SMN2KDM4E
SCHEMBL27368366 0.71 GAA (0.57) ALDH1A1LMNAGAASMN1; SMN2SSTR4
SCHEMBL3761621 0.71 POLB (0.41) EPHX2GAASMN1; SMN2SSTR4SLC6A2
SCHEMBL3764748 0.70 SSTR4 (0.43) ALDH1A1LMNASMN1; SMN2HPGDSSTR4
SCHEMBL4595722 0.69 SLC6A2 (0.53) ALDH1A1SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL4595727 0.69 SLC6A2 (0.53) ALDH1A1SLC6A2SLC6A4SLC6A3MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107189197-B Comprehensive conveying pipe for high-strength insulating flame-retardant pipeline gallery 上海中塑管业有限公司 2020-05-12 CN claimed
CN-106220994-B A kind of high intensity PP-RCT anti-flaming tubular products and preparation method 刘志光 2018-06-01 CN claimed
CN-107189197-A The fire-retardant comprehensive colliery carries tubing of pipeline gallery of high-strength insulating 上海中塑管业有限公司 2017-09-22 CN claimed
CN-106220994-A A kind of high intensity PP RCT anti-flaming tubular product and preparation method 刘志光 2016-12-14 CN claimed
CN-107189197-B Comprehensive conveying pipe for high-strength insulating flame-retardant pipeline gallery 上海中塑管业有限公司 2020-05-12 CN disclosed
CN-106220994-B A kind of high intensity PP-RCT anti-flaming tubular products and preparation method 刘志光 2018-06-01 CN disclosed
CN-107189197-A The fire-retardant comprehensive colliery carries tubing of pipeline gallery of high-strength insulating 上海中塑管业有限公司 2017-09-22 CN disclosed
CN-106220994-A A kind of high intensity PP RCT anti-flaming tubular product and preparation method 刘志光 2016-12-14 CN disclosed