Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000539 | 0.93 | DPP4 (0.36) | DPP4LTA4HTRPV1RPS6KB2 | |
| SCHEMBL28000557 | 0.86 | DPP4 (0.60) | DPP4LTA4HMEN1ALDH1A1GLA | |
| SCHEMBL4422429 | 0.85 | HPGD (0.33) | ALDH1A1HPGD | |
| SCHEMBL2585296 | 0.83 | LTA4H (0.59) | DPP4LTA4HMEN1ALDH1A1GLA | |
| SCHEMBL28000384 | 0.80 | DPP4 (0.58) | DPP4LTA4HMEN1ALDH1A1GLA | |
| SCHEMBL28333549 | 0.78 | ESRRG (0.35) | TRPV1ALDH1A1MAPTHDAC6CYP2E1 | |
| SCHEMBL13419888 | 0.77 | DPP4 (0.37) | DPP4LTA4HTRPV1MEN1ALDH1A1 | |
| SCHEMBL28000380 | 0.77 | LTA4H (0.42) | DPP4LTA4HCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL13178593 | 0.77 | MAPT (0.43) | DPP4MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL706694 | 0.76 | LTA4H (0.45) | DPP4LTA4HMEN1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496962-B | A kind of Oligopoly thiophene derivative and application thereof | 南方医科大学 | 2017-01-04 | — | — | CN | disclosed |