Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.67 |
| ▸ | DPP4 | P27487 | 4/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000574 | 1.00 | LTA4H (0.67) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL28000382 | 0.98 | LTA4H (0.69) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL28000383 | 0.95 | LTA4H (0.65) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL26625918 | 0.91 | LTA4H (0.73) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL28000380 | 0.86 | LTA4H (0.42) | LTA4HDPP4 | |
| SCHEMBL28000557 | 0.83 | DPP4 (0.60) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL799496 | 0.83 | DPP4 (0.60) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL9200282 | 0.82 | LTA4H (0.96) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL28000384 | 0.82 | DPP4 (0.58) | LTA4HDPP4TAAR1ALDH1A1LMNA | |
| SCHEMBL8575618 | 0.81 | DPP4 (0.67) | LTA4HDPP4TAAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496962-B | A kind of Oligopoly thiophene derivative and application thereof | 南方医科大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-104496962-A | Oligothiophene derivative and application thereof | UNIV SOUTHERN MEDICAL | 2015-04-08 | — | — | CN | disclosed |