Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796630 | 0.74 | HTT (0.45) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29635286 | 0.69 | HTT (0.41) | HTTALDH1A1MEN1KMT2AFNTA | |
| SCHEMBL15172938 | 0.68 | HTT (0.48) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15173023 | 0.68 | HTT (0.45) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9098561 | 0.68 | PTGS2 (0.51) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15452568 | 0.68 | RXFP1 (0.67) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15172903 | 0.68 | FNTA (0.49) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15172994 | 0.68 | MEN1 (0.50) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15184977 | 0.68 | MEN1 (0.53) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28301643 | 0.67 | MAPT (0.46) | HTTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518865-A | Method for preparing 1-alkenyl indolizine derivative | 淮阴师范学院 | 2017-03-22 | — | — | CN | disclosed |