Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.40 |
| ▸ | DRD3 | P35462 | 9/20 | 0.39 |
| ▸ | DRD4 | P21917 | 7/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | DRD5 | P21918 | 5/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25769800 | 0.91 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL26233209 | 0.84 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL25769809 | 0.84 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20540002 | 0.83 | DRD2 (0.44) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL6934553 | 0.83 | MAPT (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30665126 | 0.82 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL2984151 | 0.82 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| Hydrogen Sulfide SCHEMBL27838727 | 0.81 | MAPT (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| Hydrogen Sulfide SCHEMBL28795253 | 0.81 | DRD2 (0.41) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL12265776 | 0.81 | EPAS1 (0.36) | DRD2DRD3DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132928-A | Novel anil, medical composition and its use containing described derivant | 橘生药品工业株式会社 | 2016-11-16 | — | — | CN | disclosed |