Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.59 |
| ▸ | FNTB | P49356 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219753 | 0.78 | FNTA (0.53) | FNTAFNTBNPC1RAB9AL3MBTL1 | |
| SCHEMBL28115157 | 0.78 | FNTA (0.44) | FNTAFNTBNPC1RAB9AL3MBTL1 | |
| SCHEMBL6219974 | 0.76 | ALDH1A1 (0.47) | FNTAFNTBNPC1RAB9AL3MBTL1 | |
| SCHEMBL31365956 | 0.75 | NPC1 (0.76) | FNTAFNTBNPC1RAB9ACGAS | |
| SCHEMBL30733922 | 0.72 | POLB (0.46) | FNTAFNTBNPC1RAB9AMAPT | |
| SCHEMBL27004533 | 0.71 | FNTA (0.49) | FNTAFNTBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL27004463 | 0.70 | FNTA (0.55) | FNTAFNTBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL6221126 | 0.70 | NPC1 (0.48) | FNTAFNTBNPC1RAB9AL3MBTL1 | |
| Benzophenone SCHEMBL11756762 | 0.68 | ATM (0.67) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10362791 | 0.68 | ALDH1A1 (0.57) | FNTAFNTBL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518865-B | Preparation method of 1-alkenyl indolizine derivative | 淮阴师范学院 | 2020-04-14 | — | — | CN | disclosed |
| CN-106518865-A | Method for preparing 1-alkenyl indolizine derivative | 淮阴师范学院 | 2017-03-22 | — | — | CN | disclosed |