Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704825 | 0.85 | PDE10A (0.59) | ALDH1A1KMT2APDE10AMAPTKDM4E | |
| SCHEMBL28115678 | 0.81 | LTA4H (0.46) | BTKALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL28326515 | 0.80 | MAPT (0.56) | ALDH1A1KMT2APDE10AMAPTKDM4E | |
| SCHEMBL28327765 | 0.77 | FYN (0.43) | ALDH1A1KMT2APDE10AMAPTKDM4E | |
| SCHEMBL5641149 | 0.76 | LTA4H (0.50) | BTKALDH1A1MAPTKDM4ECYP2C9 | |
| SCHEMBL28265738 | 0.72 | IDO1 (0.48) | ALDH1A1KMT2AMAPTHPGDMEN1 | |
| SCHEMBL28326514 | 0.70 | SMN1; SMN2 (0.51) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL9796767 | 0.70 | LTA4H (0.55) | BTKALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL14805205 | 0.69 | KDM4E (0.51) | BTKALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL17424258 | 0.68 | LTA4H (0.42) | ALDH1A1KMT2APDE10AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117154-B | A kind of neighbour's aryloxy group -1,4- diaryl -1,2,3- triazole derivatives and its preparation method and application | 昆明理工大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-106117154-A | A kind of adjacent aryloxy group 1,4 diaryl 1,2,3 triazole derivatives and its preparation method and application | 昆明理工大学 | 2016-11-16 | — | — | CN | disclosed |