SCHEMBL28115683

SCHEMBL28115683

O=C(O)c1cc(N=Nc2ccc(O)cc2)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.85
KMT2A Q03164 6/20 0.85
BLVRB P30043 2/20 0.85
KDR P35968 2/20 0.85
PDE4A P27815 1/20 0.85
HTT P42858 1/20 0.85
TDP1 Q9NUW8 4/20 0.80
THRB P10828 2/20 0.80
RECQL P46063 2/20 0.80
APP P05067 1/20 0.80
BLM P54132 1/20 0.80
PHLPP2 Q6ZVD8 5/20 0.69
ALDH1A1 P00352 4/20 0.69
PTGS2 P35354 3/20 0.69
CYP2C9 P11712 3/20 0.69
TSHR P16473 2/20 0.69
HSD17B10 Q99714 2/20 0.69
CYP2C19 P33261 2/20 0.69
PTGS1 P23219 1/20 0.69
CYP2D6 P10635 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2616097 1.00 MEN1 (0.85) MEN1KMT2ABLVRBKDRPDE4A
SCHEMBL7711260 0.95 MEN1 (0.90) MEN1KMT2ABLVRBKDRPDE4A
SCHEMBL7711257 0.95 MEN1 (0.90) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL29861404 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL25119 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL29385751 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL29378994 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL2628413 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL25118 0.92 MEN1 (1.00) MEN1KMT2ABLVRBKDRPDE4A
Olsalazine SCHEMBL29769 0.90 MEN1 (0.96) MEN1KMT2ABLVRBKDRPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117139-A A kind of enhancement mode fluorescent probe and preparation method and application 华南理工大学 2016-11-16 CN claimed
CN-106117139-A A kind of enhancement mode fluorescent probe and preparation method and application 华南理工大学 2016-11-16 CN disclosed