SCHEMBL28115700

SCHEMBL28115700

N#CCC1C=CCc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GAA P10253 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
RECQL P46063 1/20 0.32
HTR2A P28223 2/20 0.31
RET P07949 1/20 0.31
HTR2C P28335 1/20 0.31
HRH1 P35367 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7294434 0.83 ATM (0.33) MEN1KMT2AHTR2ARETHTR2C
SCHEMBL30616036 0.77 HTR2A (0.35) MEN1KMT2AHTR2ARETHTR2C
SCHEMBL11503546 0.77 HTR2A (0.35) MEN1KMT2AHTR2ARETHTR2C
SCHEMBL7608278 0.74 HTR2A (0.34) HTR2AHRH1
SCHEMBL11010687 0.74 SLC22A1 (0.42) HTR2AHRH1
SCHEMBL8215822 0.70 CYP2D6 (0.36) HTR2AHTR2CHRH1
SCHEMBL11026480 0.69 MEN1 (0.32) IDO1GAAMEN1KMT2ARECQL
SCHEMBL6970317 0.69 HTR2A (0.32) HTR2AHRH1
SCHEMBL16061146 0.67 HTR2A (0.42) HTR2A
SCHEMBL2525691 0.66 HTR2A (0.35) GAAHTR2ARETHTR2CHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543034-A A kind of method of 7 methoxynaphthalene acetonitriles of synthesis 苏州弘森药业股份有限公司 2017-03-29 CN disclosed