Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215822 | 0.83 | CYP2D6 (0.36) | HTR2AHRH1 | |
| SCHEMBL7608278 | 0.77 | HTR2A (0.34) | HTR2AHRH1 | |
| SCHEMBL30616036 | 0.73 | HTR2A (0.35) | HTR2AHRH1 | |
| SCHEMBL11503546 | 0.73 | HTR2A (0.35) | HTR2AHRH1 | |
| SCHEMBL11010687 | 0.70 | SLC22A1 (0.42) | HTR2AHRH1 | |
| SCHEMBL7294434 | 0.69 | ATM (0.33) | HTR2AHRH1 | |
| SCHEMBL28115700 | 0.69 | IDO1 (0.34) | HTR2AHRH1 | |
| SCHEMBL293750 | 0.69 | — | — | |
| SCHEMBL293031 | 0.67 | — | — | |
| SCHEMBL31276808 | 0.66 | HTR2A (0.35) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848004-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5955616-A | PROSTAGLANDIN INHIBITORS | SHIONOGI & CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0848004-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |