Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Nitrobenzaldehyde SCHEMBL8619338 | 0.83 | MAPT (0.51) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL2885741 | 0.83 | ERN1 (0.57) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL5162106 | 0.80 | ERN1 (0.44) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL5816489 | 0.76 | ERN1 (0.57) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL7811549 | 0.76 | ERN1 (0.47) | ERN1MAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL7510757 | 0.75 | ERN1 (0.74) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8583620 | 0.75 | ERN1 (0.51) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8583623 | 0.75 | ERN1 (0.51) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10510863 | 0.75 | ERN1 (0.51) | ERN1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL17795763 | 0.74 | MAPT (0.41) | ERN1MAPTALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187904-A | 2-phenylimidazole analog derivative containing propioloyl amido and preparation method thereof and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2016-12-07 | — | — | CN | disclosed |