Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27042302 | 0.85 | TSHR (0.69) | TSHRTDP1CYP3A4ALDH1A1MAPK1 | |
| Triethyl Phosphate SCHEMBL28182460 | 0.81 | TSHR (0.87) | TSHRTDP1CYP3A4MEN1POLB | |
| Triethyl Phosphate SCHEMBL28023664 | 0.81 | TSHR (1.00) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| Triethyl Phosphate SCHEMBL27822049 | 0.81 | TSHR (1.00) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| Triethyl Phosphate SCHEMBL21887 | 0.81 | TSHR (1.00) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| Triethyl Phosphate SCHEMBL1332591 | 0.81 | TSHR (1.00) | TSHRTDP1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL4860767 | 0.80 | TSHR (0.42) | TSHRTDP1CYP3A4ALDH1A1MAPK1 | |
| Triethyl Phosphate SCHEMBL4555110 | 0.79 | TSHR (0.56) | TSHRMEN1POLBKMT2AACHE | |
| SCHEMBL2534198 | 0.79 | TSHR (0.40) | TSHRTDP1CYP3A4ALDH1A1MAPK1 | |
| Ethyl Pyrophosphate SCHEMBL31169617 | 0.79 | ACHE (0.46) | TSHRTDP1MEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536623-B | Composition | 日本梅克特隆株式会社 | 2018-11-30 | — | — | CN | disclosed |
| CN-106536623-A | Composition | 日本梅克特隆株式会社 | 2017-03-22 | — | — | CN | disclosed |