Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decylamine SCHEMBL10968806 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Lactic Acid SCHEMBL28836545 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hexadecylamine SCHEMBL9502522 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL5596111 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Lactic Acid SCHEMBL1837462 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Tetradecylamine SCHEMBL17498692 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octadecylamine SCHEMBL1136859 | 1.00 | DNM1 (0.56) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL29226540 | 0.98 | DNM1 (0.54) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL28272947 | 0.96 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Lactic Acid SCHEMBL11068074 | 0.91 | TP53 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164040-B | High-performance water dilution type oiliness additive for the application of polymetallic intermetallic composite coating | 埃瑟克斯化学有限责任公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-106164040-A | The high-performance water dilution type oiliness additive applied for polymetallic intermetallic composite coating | 埃瑟克斯化学有限责任公司 | 2016-11-23 | — | — | CN | disclosed |