Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116075 | 1.00 | PPARA (0.45) | PPARAPTPN1ACEBCL2PPARG | |
| SCHEMBL16178609 | 0.91 | KLK5 (0.42) | PPARAPTPN1ACEBCL2PPARG | |
| SCHEMBL16178610 | 0.91 | KLK5 (0.42) | PPARAPTPN1ACEBCL2PPARG | |
| SCHEMBL14714189 | 0.81 | BCL2 (0.48) | PPARAPTPN1ACEBCL2CTSS | |
| SCHEMBL14699538 | 0.81 | KMT2A (0.46) | PPARAPTPN1ACESYKYAP1 | |
| SCHEMBL14699539 | 0.78 | KMT2A (0.47) | PPARASYKYAP1KLK5LTA4H | |
| SCHEMBL14699537 | 0.78 | KMT2A (0.47) | PPARASYKYAP1KLK5LTA4H | |
| SCHEMBL16178663 | 0.78 | KMT2A (0.47) | PPARASYKYAP1KLK5LTA4H | |
| SCHEMBL16178662 | 0.78 | KMT2A (0.47) | PPARASYKYAP1KLK5LTA4H | |
| SCHEMBL16188947 | 0.77 | LTA4H (0.40) | YAP1KLK5LTA4HCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906743-B | The compound being combined with blood-platelet specific glycoprotein iib/iiia and the purposes of its thrombus imaging | 皮拉莫尔影像股份公司 | 2016-12-28 | — | — | CN | disclosed |