Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438167 | 0.81 | ACP1 (0.40) | ACP1L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL10077023 | 0.81 | PARP1 (0.49) | ACP1ALDH1A1LMNACCR1CCR5 | |
| SCHEMBL23421555 | 0.77 | ACP1 (0.38) | ACP1KDM4ECCR1CCR5CCR8 | |
| SCHEMBL19386400 | 0.77 | ATM (0.38) | ACP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1272770 | 0.75 | ACP1 (0.45) | ACP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1272773 | 0.75 | ACP1 (0.45) | ACP1ALDH1A1KDM4ECCR1CCR5 | |
| SCHEMBL276492 | 0.75 | MEN1 (0.47) | ACP1RIPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL701411 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ALMNACYP2A6 | |
| SCHEMBL30831434 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ALMNACYP2A6 | |
| SCHEMBL1272081 | 0.73 | ACP1 (0.43) | ACP1ALDH1A1KDM4EKMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255689-A | Heteroaryl syk inhibitors | 勃林格殷格翰国际有限公司 | 2016-12-21 | — | — | CN | disclosed |