Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615947 | 0.86 | FFAR4 (0.56) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL1505328 | 0.84 | MAPT (0.48) | MAPTMAPK1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14228414 | 0.82 | MAPT (0.56) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL5052312 | 0.81 | NPC1 (0.57) | MAPTHTTSMN1; SMN2TSHRHTR1A | |
| SCHEMBL6674358 | 0.81 | SMPD1 (0.56) | MAPK1HTTSMN1; SMN2HTR1AADRA1D | |
| SCHEMBL25081934 | 0.81 | MAPT (0.64) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL2912541 | 0.81 | MAPT (0.55) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL19286354 | 0.81 | ALOX5 (0.58) | MAPTMAPK1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL22894882 | 0.79 | PTGDR2 (0.58) | MAPTMAPK1TDP1L3MBTL1HTT | |
| SCHEMBL15426843 | 0.79 | FFAR4 (0.65) | MAPTMAPK1TDP1L3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106545541-B | A kind of remote control type Suporting structure hydraulic locking apparatus and its method of work | 徐州工程学院 | 2017-12-29 | — | — | CN | claimed |
| CN-106545541-A | A kind of remote control type Suporting structure hydraulic locking apparatus and its method of work | 徐州工程学院 | 2017-03-29 | — | — | CN | claimed |
| CN-106545541-B | A kind of remote control type Suporting structure hydraulic locking apparatus and its method of work | 徐州工程学院 | 2017-12-29 | — | — | CN | disclosed |
| CN-106545541-A | A kind of remote control type Suporting structure hydraulic locking apparatus and its method of work | 徐州工程学院 | 2017-03-29 | — | — | CN | disclosed |