Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | GLUL | P15104 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131909 | 0.91 | — | — | |
| SCHEMBL443115 | 0.91 | — | — | |
| SCHEMBL131910 | 0.91 | — | — | |
| SCHEMBL28880988 | 0.88 | USP2 (0.67) | USP2SLCO1B1PDE4AOR51E2SLC7A5 | |
| SCHEMBL812543 | 0.76 | USP2 (0.86) | USP2SLCO1B1PDE4AOR51E2SLC7A5 | |
| SCHEMBL7148984 | 0.76 | USP2 (0.86) | USP2SLCO1B1PDE4AOR51E2SLC7A5 | |
| Phosphoric Acid SCHEMBL1758764 | 0.76 | SLC7A5 (0.46) | USP2SLCO1B1SLC7A5 | |
| Phosphoric Acid SCHEMBL7091040 | 0.75 | USP2 (0.39) | USP2SLCO1B1PDE4APGDLMNA | |
| SCHEMBL25200032 | 0.75 | USP2 (0.52) | USP2SLCO1B1PDE4AOR51E2SLC7A5 | |
| Threonine SCHEMBL15571793 | 0.75 | USP2 (0.42) | USP2SLCO1B1SLC7A5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106370753-B | The identification and analysis method of coronary heart disease urine metabolism marker | 王喜军 | 2019-02-01 | — | — | CN | claimed |
| CN-106370753-A | Identification and analysis method for coronary heart disease urine metabolic markers | 王喜军 | 2017-02-01 | — | — | CN | claimed |
| CN-106370753-B | The identification and analysis method of coronary heart disease urine metabolism marker | 王喜军 | 2019-02-01 | — | — | CN | disclosed |
| CN-106370753-A | Identification and analysis method for coronary heart disease urine metabolic markers | 王喜军 | 2017-02-01 | — | — | CN | disclosed |