Boric Acid

Boric Acid

SCHEMBL28116595

CC(=O)c1cccnc1N.CC(C)(O)C(C)(C)O.OB(O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.53
PRKCI P41743 2/20 0.48
VCP P55072 4/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
P2RX7 Q99572 1/20 0.37
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
PRKCQ Q04759 1/20 0.35
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
AHR P35869 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1322157 0.87 NAPRT (0.68) NAPRTPRKCIVCPNOS3NOS1
SCHEMBL29489950 0.87 NAPRT (0.68) NAPRTPRKCIVCPNOS3NOS1
SCHEMBL13543168 0.75 NAPRT (0.61) NAPRTPRKCIVCPNOS3NOS1
SCHEMBL12750468 0.72 NAPRT (0.53) NAPRTPRKCINOS3NOS1NOS2
SCHEMBL8198020 0.72 NAPRT (0.73) NAPRTPRKCINOS3NOS1NOS2
SCHEMBL1292847 0.71 NAPRT (0.56) NAPRTPRKCIVCPNOS3NOS1
SCHEMBL13958741 0.71 PRKCI (0.58) NAPRTPRKCIVCPP2RX7KDM4E
SCHEMBL29407228 0.71 PRKCI (0.58) NAPRTPRKCIVCPP2RX7KDM4E
SCHEMBL29923922 0.71 NAPRT (0.56) NAPRTPRKCIVCPNOS3NOS1
SCHEMBL19226018 0.70 NAPRT (0.59) NAPRTPRKCIVCPNOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103601745-B Preparation method of commonly used acetamidopyridine boronic acid pinacol ester 大连联化化学有限公司 2017-01-18 CN disclosed